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บริษัท ศิริอินสตรูเมนท์ จำกัด  เป็นตัวแทนนำเข้าสินค้า อุปกรณ์ วิทยาศาสตร์ จากต่างประเทศ อาทิเช่นเครื่อง HPLC,GC,GCMS อีกทั้งอุปกรณ์ที่ใช้ในห้องแล็ปต่างๆ อุปกรณสิ้นเปลืองที่ใช้ภายในห้องแล็ป อุปกรณถังเก็บสารเคมีในห้องแล็ป และอื่นๆอีกมากมาย...อีกทั้งทางบริษัทยังให้บริการ ซ่อม เปลี่ยนอะไหล่  บำรุงรักษาเครื่องตามระยะเวลา และ Validate & Calibrate เครื่อง HPLC/GCทุกยี่ห้อ..จากฝ่ายบริการที่มีใบรับรอง

                                                                          


        

   

Equipment Min. Sample (mL) Capacity (L/hr)
EmulsiFlex-B15
EmulsiFlex-B15
3 15mL
(batch)
EmulsiFlex-C5
EmulsiFlex-C5
7 1-5
EmulsiFlex-C3
EmulsiFlex-C3
10 3
EmulsiFlex-D20
EmulsiFlex-D20
50 20
Equipment Min. Sample (mL) Capacity (L/hr)
EmulsiFlex-C50
EmulsiFlex-C50
25 15-50
EmulsiFlex-C55
EmulsiFlex-C55
250 55
EmulsiFlex-C160
EmulsiFlex-C160
500 160
EmulsiFlex-C1000
EmulsiFlex-C1000
5000 1000

HAAKE™ PolyLab™ OS Modular Torque Rheometer

Thermo Scientific™

The Thermo Scientific™ HAAKE PolyLab OS is a state-of-the-art measuring mixer and extruder system that is focused on the specific needs in research and development. The HAAKE PolyLab OS provides you with process-relevant material data including: Melting behavior, influence of additives, temperature stability, shear stability and melt viscosity. Furthermore, this measuring mixer and extruder system supports you in process modelling activities such as: Compounding polymers with additives to reduce flammability, viscosity, etc., scale-up extrusion processes by using different L/D ratios to extrapolate to your master process line, simulating master processes using only as little as 50g of material to optimize extrusion or mixing in respect to temperature and shear profile or extrusion of strands, profiles or films in combination with rheological or optical measurements.  More

 

 HPLC,UHPLC,SFC Columns From Japan

            

 

 

COSMOCORE 2.6PBr

  • Separate hydrophilic compounds in reversed-phase conditions
  • Retain hydrophilic compounds longer than C18
  • Greater sample loading capacity than HILIC
  • High performance similar to sub-2 µm particles with lower back pressure
Suitable Samples
  • Hydrophilic compounds
  • Nucleic acids and derivatives
  • Surfactants
  • Glycosides
  • Peptides

 

 

Separation of Hydrophilic Compounds (low retention on C18)

COSMOSIL PBr retains hydrophilic compounds stronger than C18 columns under the same reversed-phase conditions.

 

 

Separation Mechanism
Dispersion force (instantaneous dipole–induced dipole force)

London dispersion force is a weak intermolecular force that results from dipoles temporarily induced by random unsymmetrical electron positions in two adjacent atoms, also known as instantaneous dipole–induced dipole force. It is present in all molecules regardless of polarity. Compounds with high polarizability have stronger dispersion force.

Compounds with stronger dispersion force
  • Larger and heavier molecules
  • Molecules with larger and heavier atoms (e.g. from weakest to strongest in halogens, F2, Cl2, Br2, and I2)
  • Molecules with delocalized electrons and resonance (e.g. aromatic compounds)

COSMOSIL PBr column is packed with pentabromobenzyl-bonded silica that enables separation by dispersion force interaction.


Comparison to HILIC

Both columns are suitable for analysis of hydrophilic compounds, but they have different properties.

  PBr  HILIC 
Separation
Mode
 Reversed Phase  Hydrophilic Interaction (HILIC)
Features
  • Simple mobile phase conditions compared to HILIC.
  • Strong eluent: organic (methanol) Weak eluent: water
  • Low peak distortion with water-based samples; usable with large injection volumes of dilute samples.
  • Some hydrophilic compounds are not retained well.
  • Retains hydrophilic compounds that would not be retained by C18 columns.
  • Strong eluent: water Weak eluent: organic (acetonitrile)
  • Peak distortion occurs with large volumes of samples dissolved in water. 

 

 

 

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