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SMT Columns

 

Separation Methods Technologies, Inc. (SMT) Profile                   Amazon.com: SMT O-5-100/10 Series O Reversed- Phase C8 HPLC Column, 5 µm  Particle Size, 100Å Pore Size: Industrial & Scientific

Separation Methods Technologies, Inc. (SMT) manufactures a full variety of capillary, UPLC, UHPLC, HPLC, LPLC, SFC, GPC, SEC and other chromatography columns and resins for all methods development, validation, and scale up needs.

SMT has built a reputation as a manufacturer of the highest quality bulk packing material. We offer a wide selection of silica sizes of various pore dimensions, for various chromatographic applications. The Horizontal Polymerized Bonded Phase packing material offers the benefits of maximized silica life, which reduces manufacturing down time, waste disposal, and increased overall efficiency.

 

USP L Column Listing

The following chart has been provided as a guide to selecting HPLC columns which meet the specifications set forth in the United States Pharmacopeia [USP], which provides guidelines for the separation of related compounds.
 
It is important to note that, in many cases, USP column specifications are so broad that several (or many) column types actually meet the basic specications. For example, L1 specification calls for a column consisting of silica packing material, 5 or 10µm in diameter, bonded with octadecyl (C18) silane. However, a limited number of available C18 columns will actually perform the desired separation.
 
SMT offers a variety of columns for each category. These columns are representative of the wide range of selectivities available for each bonded phase. The packing materials vary in particle size, pore size, surface area, carbon load, hydrophobicity, bonded phase coverage or density, and other characteristics. Refer to the catalog for description and characteristics of a specific column of interest.
 

 

 

United States Pharmacopeia [USP]
Column Description Column(s)
L1 Octadecylsilane chemically bonded to porous or non-porous silica or ceramic microparticles, 1.5 to 10µm in diameter OD
ODL
Elite C18
Symplex C18
Supreme C18
AquSep C18
L2 Octadecylsilane (C18) chemically bonded to silica gel of a controlled surface porosity, 30 to 50 µm in diameter BOD Bulk Packings
BODL Bulk Packings
L3 Porous silica particles, 1.5 to 10µm in diameter S
L4 Silica gel of controlled surface porosity bonded to a solid spherical core, 30 to 50µm in diameter BS Bulk Packings
L7 Octylsilane chemically bonded to totally or superficially porous silica particles, 1.5 to 10µm in diameter O
OL
Elite C8
L8 Aminopropylsilane chemically bonded to totally porous silica gel support, 1.5 to 10µm in diameter AP (NH2)
L9 Porous silica gel having a chemically bonded, strongly acidic cation-exchange coating, 3 to 10µm in diameter SCX
L10 Nitrile groups chemically bonded to porous silica particles, 1.5 to 10µm in diameter CP (CN)
L11 Phenyl groups chemically bonded to porous silica particles, 1.5 to 10µm in diameter Phen1
Phen2
L12 A strong anion-exchange packing made by chemically bonding a quaternary amine to a solid silica spherical core, 30 to 50µm in diameter BSAX Bulk Packings
L13 Trimethylsilane chemically bonded to porous silica particles, 3 to 10µm in diameter MEB1 C1
L14 Silica gel having a chemicallly bonded, strongly basic quaternary ammonium anion-exchange coating, 5 to 10µm in diameter SAX
L15 Hexylsilane chemically bonded to totally porous silica particles, 3 to 10µm in diameter Hex C6
L16 Dimethylsilane chemically bonded to porous silica particles, 5 to 10µm in diameter MEB2-DM C2
L18 Amino and cyano groups chemically bonded to porous silica particles, 3 to 10µm in diameter AP-CP
L20 Dihydroxypropane groups chemically bonded to porous silica or hybrid particles, 1.5 to 10µm in diameter DIOL2
L26 Butylsilane chemically bonded to totally porous silica particles, 1.5 to 10µm in diameter MEB4 C4
L27 Porous silica particles, 30 to 50µm in diameter BS Bulk Packings
L30 Ethyl silane chemically bonded to 3-10µm porous silica MEB2 C2
L40 Cellulose tris-3,5-dimethylphenylcarbamate bonded on porous silica, 5-20µm ChiralSep1
L41 Immobilised alpha-1-acid glycoprotein on spherical silica particles, 5µm in diameter ChiralSepAGP
L42 Octylsilane and octadecylsilane groups chemically bonded to porous silica particles, 5µm in diameter ODO
L43 Pentafluorophenyl groups chemically bonded to silica particles 5 to 10µm in diameter C6F5
L44 Spherical silica substrate that has been bonded with a cationic exchanger, sulphonic L44 acid functionality in addition to a conventional reversed phase C8 functionality SCX-O
L52 Strong Cation Exchange resin made of porous silica with sulfopropyl groups, 5 to 10µm in diameter SCX
L56 Propyl silane chemically bonded to totally porous silica particles, 3 to 10µm in diameter Pro
L57 Chiral recognition protein, ovomucoid, chemically bonded to silica particles, about 5 µm in diameter, with pore size of 120Å CIB Ovomucoid
L59 Packing having the capacity to separate proteins by molecular weight over the range of 10 to 500 kDa. It is spherical (10 µm), silica-based, and processed to provide hydrophilic characteristics and pH stability SMTgel Diol
L60 Spherical porous silica gel, 3 or 5 µm diameter, the surface of which has been covalently modified with alkyl amide groups AquSep2
L62 C30 silane bonded phase on a fully porous spherical silica, 5-10µm in diameter TA
L63 Glycopeptide teicoplanin linked through multiple covalent bonds to spherical silica CIB TE
L70 Cellulose tris(phenyl carbamate) coated on 5-10µm porous silica ChiralSep2
L80 Cellulose tris(4-methylbenzoate)-coated, porous, spherical, silica particles, 5 to 20 µm in diameter ChiralSep3
L85 A silane ligand that consists of both reversed-phase (an alkyl chain longer than C8) and weak cation-exchange (carboxyl groups) functional groups chemically bonded to porous or non-porous particles, 1.0 to 50 µm in diameter WCX-O
L93 Cellulose tris(3,5-dimethylpheylcarbamate) reversed phase chiral stationary phase coated on 3 or 5 µm silica gel particles ChiralSep1
L107 Cellulose tris(4-methylbenzoate)-coated porous spherical particles, 3 to 5 µm in diameter ChiralSep3
Unclassified Dodecyl silane bonded on 5-10µm porous silica DD
Unclassified Proprietary strong cation exchange groups on 5-50µm Porous silica MetalSep